Multiple nutritional and gut microbial factors associated with allergic rhinitis: the Hitachi Health Study.

ABSTRACT: Several studies suggest the involvement of dietary habits and gut microbiome in allergic diseases. However, little is known about the nutritional and gut microbial factors associated with the risk of allergic rhinitis (AR). We recruited 186 participants with symptoms of AR and 106 control subjects without symptoms of AR at the Hitachi Health Care Center, Japan. The habitual consumption of 42 selected nutrients were examined using the brief-type self-administered diet history questionnaire. Faecal samples were collected and subjected to amplicon sequencing of the 16S ribosomal RNA gene hypervariable regions. Association analysis revealed that four nutrients (retinol, vitamin A, cryptoxanthin, and copper) were negatively associated with AR. Among 40 genera examined, relative abundance of Pre

SUBMITTER: Sahoyama Y 

PROVIDER: S-EPMC8888718 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature