Prenatal and early life exposure to air pollution and the incidence of Kawasaki disease.

ABSTRACT: Kawasaki disease (KD) is the most common form of acquired pediatric cardiac disease in the developed world. However, its etiology is still unclear. Epidemiological studies have shown that air pollution is a plausible risk factor in stimulating oxidative stress, inducing inflammation and causing autoimmune diseases. This study aims to assess the connections between prenatal and early life air pollution exposure to the incidence of KD. The main data source of this nationwide longitudinal study was the National Health Insurance Research Database (NHIRD) of Taiwan. NHIRD was linked with Taiwan Maternal and Child Health Database to establish the link between mothers and children. In total, 4192 KD cases involving children under 6 years of age were identified between January 2004 and December 20

SUBMITTER: Kuo NC 

PROVIDER: S-EPMC8888747 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature