Validation of UK Biobank data for mental health outcomes: A pilot study using secondary care electronic health records.

ABSTRACT: UK Biobank (UKB) is widely employed to investigate mental health disorders and related exposures; however, its applicability and relevance in a clinical setting and the assumptions required have not been sufficiently and systematically investigated. Here, we present the first validation study using secondary care mental health data with linkage to UKB from Oxford - Clinical Record Interactive Search (CRIS) focusing on comparison of demographic information, diagnostic outcome, medication record and cognitive test results, with missing data and the implied bias from both resources depicted. We applied a natural language processing model to extract information embedded in unstructured text from clinical notes and attachments. Using a contingency table we compared the demographic information r

SUBMITTER: Li Z 

PROVIDER: S-EPMC8889024 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature