Efficacy of covid-19 vaccines in immunocompromised patients: systematic review and meta-analysis.

ABSTRACT:

Objective

To compare the efficacy of covid-19 vaccines between immunocompromised and immunocompetent people.

Design

Systematic review and meta-analysis.

Data sources

PubMed, Embase, Central Register of Controlled Trials, COVID-19 Open Research Dataset Challenge (CORD-19), and WHO covid-19 databases for studies published between 1 December 2020 and 5 November 2021. ClinicalTrials.gov and the WHO International Clinical Trials Registry Platform were searched in November 2021 to identify registered but as yet unpublished or ongoing studies.

Study selection

Prospective observational studies comparing the efficacy of covid-19 vaccination in immunocompromised and immunocompetent participants.

Methods

A frequentist random effects meta-analysis was used to separa

SUBMITTER: Lee ARYB 

PROVIDER: S-EPMC8889026 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature