Head transcriptome profiling of glossiphoniid leech (Helobdella austinensis) reveals clues about proboscis development.

ABSTRACT: Cephalization refers to the evolutionary trend towards the concentration of neural tissues, sensory organs, mouth and associated structures at the front end of bilaterian animals. Comprehensive studies on gene expression related to the anterior formation in invertebrate models are currently lacking. In this study, we performed de novo transcriptional profiling on a proboscis-bearing leech (Helobdella austinensis) to identify differentially expressed genes (DEGs) in the anterior versus other parts of the body, in particular to find clues as to the development of the proboscis. Between the head and the body, 132 head-specific DEGs were identified, of which we chose 11 to investigate their developmental function during embryogenesis. Analysis of the spatial expression of these g

SUBMITTER: Kwak HJ 

PROVIDER: S-EPMC8889196 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature