Knee joint distraction results in MRI cartilage thickness increase up to 10 years after treatment.

ABSTRACT:

Objectives

Knee joint distraction (KJD) has been shown to result in long-term clinical improvement and short-term cartilage restoration in young OA patients. The objective of the current study was to evaluate MRI cartilage thickness up to 10 years after KJD treatment, using a 3D surface-based approach.

Methods

Twenty end-stage knee OA patients were treated with KJD. MRI scans (1.5 T) were performed before and at 1, 2, 5, 7, and 10 years after treatment. Tibia and femur cartilage segmentation and registration to a canonical surface were performed semi-automatically. Statistical parametric mapping with linear mixed models was used to analyse whole-joint changes. The influence of baseline patient characteristics was analysed with statistical parametric mapping using linear regr

SUBMITTER: Jansen MP 

PROVIDER: S-EPMC8889280 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature