Ontology highlight
ABSTRACT:
SUBMITTER: Zhang S
PROVIDER: S-EPMC8889291 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
Zhang Su S Li Guobao G Bi Jing J Guo Qinglong Q Fu Xiangdong X Wang Wenfei W Liu Shuyan S Xiao Guohui G Ou Min M Zhang Juanjuan J He Xing X Li Fang F Li Guanqiang G Feng Carl G CG Chen Xinchun X Zhang Guoliang G
The Journal of infectious diseases 20220301 5
Previous studies demonstrated that transforming growth factor (TGT) β1 plays an immunosuppressive role in clinical tuberculosis. However, the contribution of TGF-β1 gene polymorphisms to human tuberculosis susceptibility remains undetermined. In this study, we showed that single-nucleotide polymorphisms (SNPs) in TGF-β1 gene were associated with increased susceptibility to tuberculosis in the discovery cohort (1533 case patients and 1445 controls) and the validation cohort (832 case patients and ...[more]