Development of Cancer Among Patients With Pediatric-Onset Inflammatory Bowel Disease: A Meta-analysis of Population-Based Studies.

ABSTRACT:

Importance

Because the incidence of pediatric-onset inflammatory bowel disease (IBD) is increasing, knowledge of the long-term risk of cancer in this patient population is required.

Objective

To evaluate the relative rate of cancer among patients with pediatric-onset IBD.

Data sources

A comprehensive systematic search was performed of MEDLINE and Embase from the date of database inception to October 31, 2021.

Study selection

All unselected, population-based cohort studies of pediatric-onset IBD assessing the risk of cancer were included. Tertiary center referrals and insurance database studies were excluded. All articles were assessed by 2 independent reviewers.

Data extraction and synthesis

The study followed the Preferred Reporting Items for Systematic

SUBMITTER: Elmahdi R 

PROVIDER: S-EPMC8889462 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature