Neurocognitive impairments and brain abnormalities resulting from opioid-related overdoses: A systematic review.

ABSTRACT:

Background

Non-fatal opioid-related overdoses have increased significantly over the past two decades and there have been increasing reports of brain injuries and/or neurocognitive impairments following overdose events. Limited preclinical research suggests that opioid overdoses may cause brain injury; however, little is known about such injuries in humans. The purpose this systematic review is to summarize existing studies on neurocognitive impairments and/or brain abnormalities associated with an opioid-related overdose in humans.

Methods

PubMed, Web of Science, Ovid MEDLINE and PsyINFO were searched, without year restrictions, and identified 3099 articles. An additional 24 articles were identified by reviewing references. Articles were included if they were published in En

SUBMITTER: Winstanley EL 

PROVIDER: S-EPMC8889511 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature