Circulating chemerin levels in metabolic-associated fatty liver disease: a systematic review and meta-analysis.

ABSTRACT:

Background and objectives

Chemerin is a brand-new adipokine that has been linked to both inflammation and metabolic dysfunction. Even though a rising number of studies have connected chemerin to metabolic-associated fatty liver disease (MAFLD), formerly referred to as non-alcoholic fatty liver disease (NAFLD), this association has been controversial.

Methods

A comprehensive literature search was undertaken up to February 1, 2022, in the PubMed, Embase, Web of Science, CNKI, WANFANG, and CBM library databases. Circulating chemerin levels were obtained and summarized using the standardized mean difference (SMD) and 95% confidence interval (CI). Subgroup and meta-regression analyses were conducted to examine the possibility of heterogeneity.

Results

A total of 17 studies

SUBMITTER: Ren Q 

PROVIDER: S-EPMC8889738 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature