Wheel-Running Facilitates Phase Advances in Locomotor and Peripheral Circadian Rhythm in Social Jet Lag Model Mice.

ABSTRACT: The circadian clock maintains our health by controlling physiological functions. Social jet lag is one factor that can disrupt the body clock. This is caused by the difference in sleeping hours between weekdays when we live according to social time and holidays when we live according to our body clock. The body clock can be altered by exercise, nutrition, and stress, and several studies have reported that these factors can be used to improve a disturbed body clock. Here we focused on exercise and examined whether continuous wheel-running could improve the disordered body clock in a mouse model that mimics social jet lag. The results showed that the wheel-running exercise group showed faster synchronization of the onset of activities on weekdays which had been delayed by social jet lag and

SUBMITTER: Oneda S 

PROVIDER: S-EPMC8890682 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature