Spherical Nucleic Acids: Integrating Nanotechnology Concepts into General Chemistry Curricula.

ABSTRACT: Nanoscience and technology research offer exciting avenues to modernize undergraduate-level General Chemistry curricula. In particular, spherical nucleic acid (SNA) nanoconjugates, which behave as "programmable atom equivalents" (PAEs) in the context of colloidal crystals, are one system that one can use to reinforce foundational concepts in chemistry including matter and atoms, the Periodic Table, Lewis dot structures and the octet rule, valency and valence-shell electron-pair repulsion (VSEPR) theory, and Pauling's rules, ultimately leading to enriching discussions centered on materials chemistry and biochemistry with key implications in medicine, optics, catalysis, and other areas. These lessons connect historical and modern concepts in chemistry, relate course content to current profes

SUBMITTER: Petrosko SH 

PROVIDER: S-EPMC8890693 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature