Clinical characteristics, time course, and outcomes of major bleeding according to bleeding site in patients with venous thromboembolism.

ABSTRACT:

Background

Bleeding is the most dreaded complication of anticoagulant therapy for acute venous thromboembolism (VTE). Limited data exist about patient characteristics, time course and outcomes of major bleeding, according to the bleeding site.

Methods

We used the data from the Registro Informatizado Enfermedad TromboEmbólica (RIETE) registry (03/2001-07/2018) and identified patients who suffered from major bleeding during anticoagulation. We assessed patient characteristics, time course, and 30-day outcomes including mortality, re-bleeding, and VTE recurrences, according to bleeding site.

Results

Among 78,136 patients with VTE receiving anticoagulation, 2244 (2.9%) suffered from major bleeding (gastrointestinal in 800, intracranial in 417, hematoma in 410, genitourina

SUBMITTER: Bikdeli B 

PROVIDER: S-EPMC8891056 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature