Health-related Quality of Life for Patients Undergoing Radical Cystectomy: Results of a Large Prospective Cohort.

ABSTRACT:

Background

Radical cystectomy (RC) has the potential for profound changes to health-related quality of life (HRQOL).

Objective

To evaluate a broad range of HRQOL outcomes in a large RC cohort.

Design, setting, and participants

A single-center prospective study enrolled RC patients from 2008 to 2014. We collected 14 separate patient-reported outcome measures at the presurgical visit and at 3, 6, 12, 18, and 24 mo after RC.

Outcome measurements and statistical analysis

To visualize the patterns of recovery over time across domains, we used generalized estimating equations (GEEs) with nonlinear terms. Given substantial differences in patient selection for the type of urinary diversion, we separately modeled longitudinal HRQOL within conduit and continent diversion

SUBMITTER: Clements MB 

PROVIDER: S-EPMC8891075 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature