Treatment regimens for neuromyelitis optica spectrum disorder attacks: a retrospective cohort study.

ABSTRACT:

Background

Neuromyelitis optica spectrum disorder (NMOSD) attacks require an urgent probabilistic anti-inflammatory therapeutic strategy. As inadequately treated attacks result in disability, there is a need to identify the optimal attack-treatment regimen. Our study aimed to identify predictors of outcome after a first attack in patients with an NMOSD presentation and propose the best treatment strategy.

Methods

We performed a retrospective cohort study on the French national NMOSD registry (NOMADMUS), a nested cohort of the French multiple sclerosis observatory (OFSEP) recruiting patients with NMOSD presentations in France. We studied the first attack for any independent locations of clinical core characteristic of NMOSD, in treatment-naïve patients. The primary outcome wa

SUBMITTER: Demuth S 

PROVIDER: S-EPMC8892703 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature