Metal-mixtures in toenails of children living near an active industrial facility in Los Angeles County, California.

ABSTRACT:

Background

Children residing in communities near metalworking industries are vulnerable to multiple toxic metal exposures. Understanding biomarkers of exposure to multiple toxic metals is important to characterize cumulative burden and to distinguish potential exposure sources in such environmental justice neighborhoods impacted by industrial operations. Exposure to metal mixtures has not been well-characterized among children residing in the United States, and is understudied in communities of color.

Methods

In this study we used toenail clippings, a noninvasive biomarker, to assess exposure to arsenic (As), cadmium (Cd), mercury (Hg), manganese (Mn), lead (Pb), antimony (Sb), selenium (Se), and vanadium (V). We used nonnegative matrix factorization (NMF) to identify "sourc

SUBMITTER: Van Horne YO 

PROVIDER: S-EPMC8893014 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature