The effect of cognitive function and central nervous system depressant use on mortality-A prospective observational study of previously hospitalised older patients.

ABSTRACT:

Background

Older patients are often users of prolonged Central Nervous System Depressants (CNSD) (Z-hypnotics, benzodiazepines and opioids), which may be associated with reduced cognition. The long-term effects of CNSD use and reduced cognitive function in older patients are unclear. The aim of this study was to examine whether cognitive function and CNSD use at baseline hospitalisation were associated with all-cause mortality two years after discharge.

Methods

We conducted a prospective observational study, including baseline data (2017-2018) from previously hospitalised older patients (65-90 years), assessing all-cause mortality two years after discharge. We used logistic regression to assess the primary outcome, all-cause mortality two years after baseline hospitalisation

SUBMITTER: Siddiqui TG 

PROVIDER: S-EPMC8893618 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature