Identification of Hsp70 modulators through modeling of the substrate binding domain.

ABSTRACT: The design, synthesis and preliminary activity of small molecular weight modulators of the heat shock protein 70 (Hsp70) are described. The compounds provide a starting point for the synthesis of novel tools to decipher Hsp70 biology.

SUBMITTER: Haney CM 

PROVIDER: S-EPMC8894028 | biostudies-literature | 2009 Jul

REPOSITORIES: biostudies-literature