Clinical Speech fMRI in Children and Adolescents : Development of an Optimal Protocol and Analysis Algorithm.

ABSTRACT:

Purpose

In patients with drug-resistant focal epilepsy, surgical resection is often the only treatment option to achieve long-term seizure control. Prior to brain surgery involving potential language areas, identification of hemispheric language dominance is crucial. Our group developed and validated a functional magnetic resonance imaging (fMRI) battery of four pediatric language tasks. The present study aimed at optimizing fMRI data acquisition and analysis using these tasks.

Methods

We retrospectively analyzed speech fMRI examinations of 114 neuropediatric patients (age range 5.8-17.8 years) who were examined prior to possible epilepsy surgery. In order to evaluate hemispheric language dominance, 1-4 language tasks (vowel identification task VIT, word-chain task WCT, beep

SUBMITTER: Krafft H 

PROVIDER: S-EPMC8894226 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature