Socioeconomic disparities and household crowding in association with the fecal microbiome of school-age children.

ABSTRACT: The development of the gut microbiome occurs mainly during the first years of life; however, little is known on the role of environmental and socioeconomic exposures, particularly within the household, in shaping the microbial ecology through childhood. We characterized differences in the gut microbiome of school-age healthy children, in association with socioeconomic disparities and household crowding. Stool samples were analyzed from 176 Israeli Arab children aged six to nine years from three villages of different socioeconomic status (SES). Sociodemographic data were collected through interviews with the mothers. We used 16 S rRNA gene sequencing to characterize the gut microbiome, including an inferred analysis of metabolic pathways. Differential analysis was performed using the analys

SUBMITTER: Lapidot Y 

PROVIDER: S-EPMC8894399 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature