Organocatalytic asymmetric nitroso aldol reaction of α-substituted malonamates.

ABSTRACT: A practical enantioselective N-selective nitroso aldol reaction of α-methylmalonamates with a nitrosoarene is reported. The reaction employs the Takemoto thiourea catalyst for the induction of enantioselectivity, and the corresponding optically active oxyaminated malonamates were obtained in reasonably good yields.

SUBMITTER: Gupta E 

PROVIDER: S-EPMC8895028 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature