Cyanine-Doped Lanthanide Metal-Organic Frameworks for Near-Infrared II Bioimaging.

ABSTRACT: Developing metal-organic frameworks (MOFs) with strong near-infrared II (NIR-II, 1000-1700 nm) emission is significant for biomedical research but highly challenging. So far there are no MOFs reported for NIR-II imaging in vivo due to their poor NIR-II emission efficiency. Herein, a strategy is proposed to prepare MOFs with strong NIR-II emission, by integrating NIR dye IR-3C and Ln³⁺ (Ln = Yb, Nd, and Er) into a same framework. IR-3C with high photon-absorption ability harvests the excitation photons and transfers energy to Ln³⁺ via a resonance energy transfer pathway, significantly enhancing the NIR-II emission of Ln³⁺ . The as-obtained Er-BTC-IR exhibits excellent NIR-IIb (1500-1700 nm) emission efficiency in aqueous phase and good biocompatibility after

SUBMITTER: Liang T 

PROVIDER: S-EPMC8895151 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature