Co-selective Pressure of Cadmium and Doxycycline on the Antibiotic and Heavy Metal Resistance Genes in Ditch Wetlands.

ABSTRACT: Abuse of heavy metals and antibiotics results in the dissemination of metal resistance genes (MRGs) and antibiotic resistance genes (ARGs). Ditch wetlands are important sinks for heavy metals and antibiotics. The relationships between bacterial communities and MRG/ARG dissemination under dual stresses of heavy metals and antibiotics remain unclear. The responses of MRGs and ARGs to the co-selective pressure of cadmium (Cd) and doxycycline (DC) in ditch wetlands were investigated after 7-day and 84-day exposures. In ecological ditches, residual rates of Cd and DC varied from 0.4 to -5.73% and 0 to -0.61%, respectively. The greatest total relative abundance of ARGs was observed in the Cd 5 mg L^-1 + DC 50 mg L^-1 group. A significant level of DC (50 mg L^-1) sig

SUBMITTER: Yu MF 

PROVIDER: S-EPMC8895241 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature