The influences of perfluoroalkyl substances on the rheumatoid arthritis clinic.

ABSTRACT:

Background

The effect of environmental factors on genetically susceptible individuals is a basic link in the pathogenesis of rheumatoid arthritis. Perfluoroalkyl substances (PFASs) are a class of synthetic organic fluorine chemicals, which have been mass-produced and widely used in the past 60 years, and also have been shown to be one of the major pollutants affecting human health. The impact of fluoride on the development of Rheumatoid Arthritis (RA) is unclear. This study explored the relationship between common fluoride and clinical manifestations of rheumatoid arthritis.

Results

A cohort of 155 patients with RA and 145 health controls in Second Affiliated Hospital of Zhejiang University School of Medicine were investigated. Serum concentrations of all fluoride detected w

SUBMITTER: Zhao Y 

PROVIDER: S-EPMC8895528 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature