Thymidine utilisation pathway is a novel phenotypic switch of Mycoplasma hominis.

ABSTRACT: Introduction. Mycoplasma hominis is a bacterium belonging to the class Mollicutes. It causes acute and chronic infections of the urogenital tract. The main features of this bacterium are an absence of cell wall and a reduced genome size (517-622 protein-encoding genes). Previously, we have isolated morphologically unknown M. hominis colonies called micro-colonies (MCs) from the serum of patients with inflammatory urogenital tract infection.Hypothesis. MCs are functionally different from the typical colonies (TCs) in terms of metabolism and cell division.Aim. To determine the physiological differences between MCs and TCs of M. hominis and elucidate the pathways of formation and growth of MCs by a comparative proteomic analysis of these two mo

SUBMITTER: Fisunov GY 

PROVIDER: S-EPMC8895549 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature