Pool-GWAS on reproductive dormancy in Drosophila simulans suggests a polygenic architecture.

ABSTRACT: The genetic basis of adaptation to different environments has been of long-standing interest to evolutionary biologists. Dormancy is a well-studied adaptation to facilitate overwintering. In Drosophila melanogaster, a moderate number of genes with large effects have been described, which suggests a simple genetic basis of dormancy. On the other hand, genome-wide scans for dormancy suggest a polygenic architecture in insects. In D. melanogaster, the analysis of the genetic architecture of dormancy is complicated by the presence of cosmopolitan inversions. Here, we performed a genome-wide scan to characterize the genetic basis of this ecologically extremely important trait in the sibling species of D. melanogaster, D. simulans that lacks cosmopolitan inversions. We performed Pool-GWAS in a S

SUBMITTER: Lirakis M 

PROVIDER: S-EPMC8895979 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature