Growth in diagnosis and treatment of primary immunodeficiency within the global Jeffrey Modell Centers Network.

ABSTRACT:

Background

Primary immunodeficiencies (PI), which include more than 450 single-gene inborn errors of immunity and may affect up to 1% of the population, are genetic disorders that impair the immune system. If not properly identified and treated, individuals with PI are subject to serious, prolonged, and sometimes life-threatening infections or autoimmunity. Despite advancements, awareness of PI remains a critical issue for physicians and the public alike, as this leads to the enhanced and expedited management of these conditions. To address this critical issue, the Jeffrey Modell Foundation (JMF) formed a global network of specialized centers. The goal of this endeavor was to raise awareness of PI to better identify, diagnose, and treat patients, reducing associated mortality and m

SUBMITTER: Quinn J 

PROVIDER: S-EPMC8896271 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature