Blood biomarkers of post-stroke depression after minor stroke at three months in males and females.

ABSTRACT:

Background

Post-stroke depression (PSD) is one of the most common neuropsychiatric complications after stroke. Studies on the underlying mechanisms and biological markers of sex differences in PSD are of great significance, but there are still few such studies. Therefore, the main objective of this study was to investigate the association of biomarkers with PSD at 3 months after minor stroke in men and women.

Methods

This was a prospective multicenter cohort study that enrolled 530 patients with minor stroke (males, 415; females, 115). Demographic information and blood samples of patients were collected within 24 h of admission, and followed up at 3 months after stroke onset. PSD was defined as a depressive disorder due to another medical condition with depressive features,

SUBMITTER: Qiu X 

PROVIDER: S-EPMC8896360 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature