MAINE: a web tool for multi-Omics feature selection and rule based data exploration.

ABSTRACT: Patinent multi-omics datasets are often characterized by a high dimensionality, however usually only for a small fraction of the features is informative, that is changes in their values is directly related to the disease outcome or patient survival. In medical sciences, in addition to a robust feature selection procedure, the ability to discover human-readable patterns in the analysed data is also desirable. To address this need, we created MAINE-Multi-omics Analysis and Exploration. The unique functionality of MAINE is the ability to discover multidimensional dependencies between the selected multi-omics features and event outcome prediction as well as patient survival probability. Learned patterns are visualized in the form of interpretable decision/survival trees and rules. MAINE is fre

SUBMITTER: Gruca A 

PROVIDER: S-EPMC8896606 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature