A simple mortality risk prediction score for viper envenoming in India (VENOMS): A model development and validation study.

ABSTRACT:

Background

Snakebite is a neglected problem with a high mortality in India. There are no simple clinical prognostic tools which can predict mortality in viper envenomings. We aimed to develop and validate a mortality-risk prediction score for patients of viper envenoming from Southern India.

Methods

We used clinical predictors from a prospective cohort of 248 patients with syndromic diagnosis of viper envenoming and had a positive 20-minute whole blood clotting test (WBCT 20) from a tertiary-care hospital in Puducherry, India. We applied multivariable logistic regression with backward elimination approach. External validation of this score was done among 140 patients from the same centre and its performance was assessed with concordance statistic and calibration plots.

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SUBMITTER: Gopalakrishnan M 

PROVIDER: S-EPMC8896694 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature