RecPD: A Recombination-aware measure of phylogenetic diversity.

ABSTRACT: A critical step in studying biological features (e.g., genetic variants, gene families, metabolic capabilities, or taxa) is assessing their diversity and distribution among a sample of individuals. Accurate assessments of these patterns are essential for linking features to traits or outcomes of interest and understanding their functional impact. Consequently, it is of crucial importance that the measures employed for quantifying feature diversity can perform robustly under any evolutionary scenario. However, the standard measures used for quantifying and comparing the distribution of features, such as prevalence, phylogenetic diversity, and related approaches, either do not take into consideration evolutionary history, or assume strictly vertical patterns of inheritance. Consequently, the

SUBMITTER: Bundalovic-Torma C 

PROVIDER: S-EPMC8896707 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature