Investigating phenotypes of pulmonary COVID-19 recovery: A longitudinal observational prospective multicenter trial.

ABSTRACT:

Background

The optimal procedures to prevent, identify, monitor, and treat long-term pulmonary sequelae of COVID-19 are elusive. Here, we characterized the kinetics of respiratory and symptom recovery following COVID-19.

Methods

We conducted a longitudinal, multicenter observational study in ambulatory and hospitalized COVID-19 patients recruited in early 2020 (n = 145). Pulmonary computed tomography (CT) and lung function (LF) readouts, symptom prevalence, and clinical and laboratory parameters were collected during acute COVID-19 and at 60, 100, and 180 days follow-up visits. Recovery kinetics and risk factors were investigated by logistic regression. Classification of clinical features and participants was accomplished by unsupervised and semi-supervised multiparameter cl

SUBMITTER: Sonnweber T 

PROVIDER: S-EPMC8896831 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature