Driving Pressure Is Associated With Outcome in Pediatric Acute Respiratory Failure.

ABSTRACT:

Objectives

Driving pressure (ratio of tidal volume over respiratory system compliance) is associated with mortality in acute respiratory distress syndrome. We sought to evaluate if such association could be identified in critically ill children.

Design

We studied the association between driving pressure on day 1 of mechanical ventilation and ventilator-free days at day 28 through secondary analyses of prospectively collected physiology data.

Setting

Medical-surgical university hospital PICU.

Patients

Children younger than 18 years (stratified by Pediatric Mechanical Ventilation Consensus Conference clinical phenotype definitions) without evidence of spontaneous respiration.

Interventions

Inspiratory hold maneuvers.

Measurements and main results

Da

SUBMITTER: van Schelven P 

PROVIDER: S-EPMC8897270 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature