Predictors of Bone Mineral Density in Kidney Stone Formers.

ABSTRACT:

Introduction

Nephrolithiasis is associated with an increased fracture risk, but predictors of bone mineral density (BMD) in stone formers (SFs) remain poorly defined.

Methods

We conducted a retrospective analysis in the Bern Kidney Stone Registry (BKSR), an observational cohort of kidney SFs. Inclusion criteria were age ≥18 years and ≥1 past stone episode. Participants with non-calcium (Ca)-containing kidney stones, a history of primary hyperparathyroidism or antiresorptive or anabolic bone treatment were excluded. Multivariable linear regression analyses were used to assess the association of blood and 24-hours urine parameters and stone composition with BMD at the lumbar spine and femoral neck.

Results

In the analysis, 504 participants were included, mean age was 46

SUBMITTER: Dhayat NA 

PROVIDER: S-EPMC8897287 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature