Development of a diagnostic model to identify patients at high risk for cerebellopontine angle lesions.

ABSTRACT:

Purpose

To develop a diagnostic model to identify patients at high risk of a CPA lesion.

Methods

A consecutive cohort of patients with AAD referred by a general practitioner, who underwent their first MRI examination of the CPA between 2005 and 2015 was included. Demographics, symptoms, findings during physical examination, and pure-tone audiometry were used as potential predictors. The presence of a CPA lesion was used as outcome.

Results

We analyzed data of 2,214 patients, detecting 73 CPA lesions in 69 (3.1%) patients. The final model contained eleven variables, namely gender [male] [OR 1.055 (95% CI 0.885-1.905)], sudden onset of hearing loss [OR 0.768 (95% CI 0.318-0.992)], gradual onset of hearing loss [OR 1.069 (95% CI 0.500-1.450)], unilateral tinnitus [OR 0.6

SUBMITTER: Hentschel M 

PROVIDER: S-EPMC8897319 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature