Quantitative evaluation of disease severity in connective tissue disease-associated interstitial lung disease by dual-energy computed tomography.

ABSTRACT:

Background

High-resolution computed tomography (HRCT) is recommended diagnosing and monitoring connective tissue disease-associated interstitial lung disease (CTD-ILD). Quantitative computed tomography has the potential to precisely assess the radiological severity of CTD-ILD, but has still been under study.

Objective

To investigate whether dual-energy computed tomography (DECT), a novel quantitative technique, can be used for quantitative severity assessment in CTD-ILD.

Methods

This cross sectional study recruited adult CTD-ILD patients who underwent DECT scans from the ICE study between October 2019 and November 2021. DECT parameters, including effective atomic number (Z_eff), lung (lobe) volume, and monochromatic CT number (MCTN) of each lung lobe, were e

SUBMITTER: Chen L 

PROVIDER: S-EPMC8897904 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature