Determinants of blood eosinophil levels in the general population and patients with COPD: a population-based, epidemiological study.

ABSTRACT:

Background

Blood eosinophils are considered a biomarker for the treatment of chronic obstructive pulmonary disease (COPD). Population-based studies are needed to better understand the determinants of the blood eosinophil count (BEC) in individuals with and without COPD.

Methods

EPISCAN II is a multicentre, cross-sectional, population-based epidemiological study aimed at investigating the prevalence and determinants of COPD in Spain. Study subjects were randomly selected from the general population, and COPD was defined by a post-bronchodilator FEV₁/FVC < 0.7. For the pre-specified outcomes related to BEC, the first 35 COPD and 35 non-COPD subjects were consecutively recruited in 12 of the participating centres with the objective of analysing 400 individuals in eac

SUBMITTER: Miravitlles M 

PROVIDER: S-EPMC8897916 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature