The role of Th17 cells in the pathogenesis and treatment of breast cancer.

ABSTRACT: Breast cancer is a severe problem worldwide due to an increase in mortality and prevalence among women. Despite early diagnostic procedures as well as advanced therapies, more investigation is required to find new treatment targets. Various factors and mechanisms, such as inflammatory conditions, can play a crucial role in cancer progression. Among them, Th17 cells are identified as effective CD4⁺ T cells that play an essential role in autoimmune diseases and inflammation which may be associated with anti-tumor responses. In addition, Th17 cells are one of the main factors involved in cancer, especially breast cancer via the inflammatory process. In tumor immunity, the exact mechanism of Th17 cells is not entirely understood and seems to have a dual function in tumor development

SUBMITTER: Karpisheh V 

PROVIDER: S-EPMC8897940 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature