Advances in stem cell therapy in Alzheimer's disease: a comprehensive clinical trial review.

ABSTRACT: Alzheimer's disease (AD) is the most common type of dementia responsible for more than 121,499 deaths from AD in 2019 making AD the sixth-leading cause in the United States. AD is a progressive neurodegenerative disorder characterized by decline of memory, behavioral impairments that affects a person's ability to function independently ultimately leading to death. The current pressing need for a treatment for (AD) and advances in the field of cell therapy, has rendered stem cell therapeutics a promising field of research. Despite advancements in stem cell technology, confirmed by encouraging pre-clinical utilization of stem cells in AD animal models, the number of clinical trials evaluating the efficacy of stem cell therapy is limited, with the results of many ongoing clinical trials on ce

SUBMITTER: Karvelas N 

PROVIDER: S-EPMC8898169 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature