Association of severity and mortality of Covid-19 cases among acute kidney injury and sexual dimorphism.

ABSTRACT:

Introduction

The outbreak of coronavirus disease 2019 (Covid-19) severely impacted global health and economic status. The native receptor-ligand interaction of Angiotensin-converting enzyme 2 (ACE2) and S protein induces host cell pathogenesis via immunosuppression.

Material and methods

The emerging evidence reports the sex disparity in Covid-19 induced mortality rate which affects abundantly men population. Although the biological interaction of Covid-19 with receptor upregulates the viral genome protein interactions and initiates the predictive multiorgan failure followed by acute kidney injury (AKI) in Covid-19 infected male population.

Conclusion

Besides, the knowledge and lessons learned from the study depict that cellular and molecular links may explain the risk

SUBMITTER: Singh MK 

PROVIDER: S-EPMC8898193 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature