Pediatric Prediction Model for Low Immunoglobulin G Level Based on Serum Globulin and Illness Status.

ABSTRACT: Hypogammaglobulinemia is a condition that requires prompt diagnosis and treatment. Unfortunately, serum immunoglobulin (Ig) measurements are not widely accessible in numerous developing countries. Serum globulin is potentially the best candidate for screening of low IgG level (IgGLo) due to its high availability, low cost, and rapid turnover time. However, multiple factors may influence the probability of prediction. Our study aimed to establish a simple prediction model using serum globulin to predict the likelihood of IgGLo in children. For retrospective data of patients who were suspected of having IgGLo, both serum IgG and globulin were simultaneously collected and measured. Potential factors interfering with serum globulin and IgG levels were investigated for their impact using bivari

SUBMITTER: Suratannon N 

PROVIDER: S-EPMC8899039 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature