Evaluation of mid- and long-term impact of COVID-19 on male fertility through evaluating semen parameters.

ABSTRACT:

Background

The coronavirus disease 2019 (COVID-19) has spread worldwide with alarming levels of spread and severity. The distribution of angiotensin converting enzyme 2 (ACE2) and transmembrane protease serine 2 (TMPRSS2) from bioinformatics evidence, the autopsy report for COVID-19 and the published study on sperm quality indicated COVID-19 could have a negative impact on male fertility. However, whether the negative impact of COVID-19 on male fertility is persistent remains unknown, which requires long-term follow-up investigation.

Methods

Semen samples were collected from 36 male COVID-19 patients with a median recovery time of 177.5 days and 45 control subjects. Then, analysis of sperm quality and alterations of total sperm number with recovery time were performed.

Re

SUBMITTER: Hu B 

PROVIDER: S-EPMC8899150 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature