A systematic review and meta-analysis of neostigmine for urinary retention after surgeries.

ABSTRACT:

Background

The aim of this research is to analyze the efficacy of neostigmine in the treatment of postoperative urinary retention (POUR).

Methods

In this research, we screened multiple databases including PubMed, EMBASE, Web of Science, and Chinese National Knowledge Infrastructure (CNKI). After a systematic search process, data extraction was conducted. Review Manager 5.2 was adopted for meta-analysis, sensitivity analysis, and bias analysis.

Results

After searching for articles, 20 eligible trials including 1,850 patients after surgery were extracted. Our results suggested that the neostigmine group had a higher effective rate for urinary retention than the Chinese traditional and physical therapy group (OR =7.47, 95% CI: 4.10-13.59, overall effect P<0.001). Further

SUBMITTER: Cao M 

PROVIDER: S-EPMC8899153 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature