Dataset Information

Internal limiting membrane packing for treatment of morning glory syndrome with rhegmatogenous retinal detachment.

ABSTRACT:

Purpose

This study aimed to report the ocular features, surgical methods, and surgical outcomes of a patient with morning glory syndrome(MGS) complicated with rhegmatogenous retinal detachment(RRD).

Observations

The patient was a 38-year-old Chinese woman with congenital cataract in her left eye and an artificial eye in her right eye. Ocular examination confirmed MGS complicated with RD in the left eye and revealed a retinal hole in the temporal margin of the optic disc. The retina successfully reattached after pars plana vitrectomy(PPV), silicone oil tamponade and laser photocoagulation, but the hole did not close and occurred obvious contractile movement. The retina did not detach again during the follow-up period. One and a half years later, silicone oil removal combined with internal limiting membrane and hyaloid or glial remnant plugging, autologous blood covering and C3F8 filling were performed, and the retinal hole was finally closed.

Conclusions and importance

This case is the first to report contractile movement of the retinal hole in a patient with MGS complicated with RD, and the hole was closed by internal limiting membrane tamponade combined with autologous blood coverage.

SUBMITTER: Shen J

PROVIDER: S-EPMC8899239 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature

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Publications

Internal limiting membrane packing for treatment of morning glory syndrome with rhegmatogenous retinal detachment.

Shen Jinyan J Chen Xuan X Gong Xuechun X Wu Zhifeng Z

American journal of ophthalmology case reports 20220302

<h4>Purpose</h4>This study aimed to report the ocular features, surgical methods, and surgical outcomes of a patient with morning glory syndrome(MGS) complicated with rhegmatogenous retinal detachment(RRD).<h4>Observations</h4>The patient was a 38-year-old Chinese woman with congenital cataract in her left eye and an artificial eye in her right eye. Ocular examination confirmed MGS complicated with RD in the left eye and revealed a retinal hole in the temporal margin of the optic disc. The retin ...[more]

PMID: 35265775

Similar Datasets

Project description:BackgroundEpiretinal membranes (ERMs) have been reported after pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD). Peeling of the internal limiting membrane (ILM) can prevent post-PPV ERM formation but has a potential negative impact on macular structure and function.PurposeTo investigate the anatomical and functional outcomes of ILM peeling during PPV for primary RRD.MethodsThis was a prospective nonrandomized study that included 60 eyes of 60 patients with a primary macula-off RRD and less than grade C proliferative vitreoretinopathy (PVR). Eyes were allocated into 2 groups; Group A underwent PPV without ILM peeling and Group B had ILM peeling. At postoperative month 6, all patients underwent retinal imaging using spectral domain optical coherence tomography (OCT) and OCT angiography and macular function was assessed using multifocal electroretinogram (mfERG). Baseline characteristics and postoperative anatomical and visual outcomes were recorded and statistically analyzed.ResultsWe enrolled 30 eyes of 30 patients in each group. In Group A, mean age was 44.6 years, while the mean age of Group B patients was 49.9 years. Postoperative LogMAR visual acuity was significantly better in Group A than in Group B (p < 0.001). ERMs were demonstrated on OCT in 13.3% of Group A and none of Group B patients (p = 0.04). Retinal dimples were found in 53.3% of Group B and none of Group A eyes (p < 0.001). OCTA showed a greater vessel density of the superficial capillary plexus (SCP) in Group A compared to Group B eyes (p = 0.046), while no difference was found regarding deep capillary vessel density (p = 0.7). Mean amplitude of mfERG P1 wave was significantly higher in Group A eyes than in Group B (p = 0.002). Both the SCP vessel density and P1 amplitude were positively correlated with visual acuity (p < 0.001).ConclusionThis study suggests that ILM peeling prevents ERM development in eyes undergoing PPV for uncomplicated macula-off RRD, but potential damage to macular structure and function were found.Trial registration Retrospectively registered on 09/24/2019 on ClinicalTrials.gov with an ID of NCT04139811.

Project description:BackgroundInternal limiting membrane (ILM) peeling during primary vitrectomy for rhegmatogenous retinal detachment (RRD) prevents the formation of postoperative macular epiretinal membrane (ERM). However, studies that compared vitrectomy with and without ILM peeling for RRD, have reported controversial outcomes.ObjectiveTo assess the efficacy of ILM peeling versus non-ILM peeling during vitrectomy for RRD by a systematic review and meta-analysis of published studies.MethodsPubMed, Medline, Web of Science, Embase databases, and the Cochrane Library were searched up to April 2018 to identify studies that compared primary vitrectomy with and without ILM peeling for RRD with at least six months follow-up. Primary outcomes were the rate of postoperative ERM formation and mean best corrected visual acuity (BCVA) change after vitrectomy. Rate of recurrence of retinal detachment (RD) was assessed as secondary outcome. Risk ratios (RRs) with 95% confidence intervals (CIs) expressed pooled results for rate of ERM formation and rate of RD recurrence in ILM peeling and non-ILM peeling groups. Pooled results for BCVA change in the two groups were expressed as Weighted Mean Difference (WMD) with 95% CIs.ResultsNine studies, one of which was a randomized controlled trial (RCT), with a total number of 404 eyes in the ILM peeling group and 365 eyes in the non-ILM peeling group, were included. The analysis from pooled data indicated a significant lower rate of postoperative ERM formation in the ILM peeling group compared to the non-ILM peeling group (9 studies, 769 eyes, RR = 0.14; CI: 0.07 to 0.28; P < 0.001). There was no statistical difference in mean BCVA change (9 studies, 769 eyes, WMD = 0.02; CI: -0.11 to 0.16; P = 0.75). Rate of recurrence of RD was lower in the ILM peeling group (6 studies, 603 eyes, RR = 0.32; CI = 0.17 to 0.61; P< 0.001).ConclusionILM peeling during vitrectomy for RRD prevents the formation of macular epiretinal membrane postoperatively and reduces the incidence of RD recurrence, but better visual outcome was not found compared to non-ILM peeling vitrectomy.

Dataset Information

Internal limiting membrane packing for treatment of morning glory syndrome with rhegmatogenous retinal detachment.

Purpose

Observations

Conclusions and importance

Publications

Internal limiting membrane packing for treatment of morning glory syndrome with rhegmatogenous retinal detachment.

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