Effect of systemic bisphosphonate administration on patients with periodontal disease: a systematic review and meta-analysis protocol.

ABSTRACT:

Introduction

Periodontal disease is a chronic oral infectious disease affecting adults worldwide as well as a lifestyle-related disease related to diabetes. Bisphosphonate is a drug often taken by patients with osteoporosis; however, it reportedly can cause jawbone necrosis. Due to its mechanism of action on bone tissue, bisphosphonate has been used topically on periodontal tissue to treat periodontal disease. However, the long-term systemic effects of bisphosphonates on periodontal tissues are unclear. This paper describes a protocol evaluating the effects of systemic bisphosphonate administration to prevent periodontal tissue destruction in patients with periodontal disease. No systematic review has attempted to summarise the evidence for systemic bisphosphonates in periodontal t

SUBMITTER: Koide Y 

PROVIDER: S-EPMC8900018 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature