Energetics for CO₂ Reduction by Molybdenum-Containing Formate Dehydrogenase.

ABSTRACT: The level of carbon dioxide in the atmosphere has increased in a dangerous way during the past century. Methods to decrease this level are therefore of high interest at present. Inspiration to do so in an efficient way could come from biological systems. Molybdenum-containing formate dehydrogenase (Mo-FDH) is one of the most interesting enzymes in this respect. For example, the reduction potential required is not very low. The normal reaction catalyzed by Mo-FDH is actually the opposite one of oxidizing formate to CO₂. However, recent electrochemical studies have shown that the reaction can be reversed by a moderate lowering of the reduction potential. The goal of the present study has been to study the full mechanism of Mo-FDH, particularly in the most interesting direction of

SUBMITTER: Siegbahn PEM 

PROVIDER: S-EPMC8900120 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature