The radiotherapy quality assurance gap among phase III cancer clinical trials.

ABSTRACT:

Purpose

Quality assurance (QA) practices improve the quality level of oncology trials by ensuring that the protocol is followed and the results are valid and reproducible. This study investigated the utilization of QA among randomized controlled trials that involve radiotherapy (RT).

Methods and materials

We searched ClinicalTrials.gov in February 2020 for all phase III oncology randomized clinical trials (RCTs). These trials were screened for RT-specific RCTs that had published primary trial results. Information regarding QA in each trial was collected from the study publications and trial protocol if available. Two individuals independently performed trial screening and data collection. Pearson's Chi-square tests analyses were used to assess factors that were associated wi

SUBMITTER: Corrigan KL 

PROVIDER: S-EPMC8900671 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature