Replacing quarantine of COVID-19 contacts with periodic testing is also effective in mitigating the risk of transmission.

ABSTRACT: The quarantine of identified close contacts has been vital to reducing transmission rates and averting secondary infection risk before symptom onset and by asymptomatic cases. The effectiveness of this contact tracing strategy to mitigate transmission is sensitive to the adherence to quarantines, which may be lower for longer quarantine periods or in vaccinated populations (where perceptions of risk are reduced). This study develops a simulation model to evaluate contact tracing strategies based on the sequential testing of identified contacts after exposure as an alternative to quarantines, in which contacts are isolated only after confirmation by a positive test. The analysis considers different number and types of tests (PCR and lateral flow antigen tests (LFA)) to identify the cost-eff

SUBMITTER: Foncea P 

PROVIDER: S-EPMC8901648 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature