Patients with low muscle mass have characteristic microbiome with low potential for amino acid synthesis in chronic liver disease.
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ABSTRACT:
SUBMITTER: Yamamoto K
PROVIDER: S-EPMC8901651 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
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Patients with low muscle mass have characteristic microbiome with low potential for amino acid synthesis in chronic liver disease.
Yamamoto Kenta K Ishizu Yoji Y Honda Takashi T Ito Takanori T Imai Norihiro N Nakamura Masanao M Kawashima Hiroki H Kitaura Yasuyuki Y Ishigami Masatoshi M Fujishiro Mitsuhiro M
Scientific reports 20220307 1
Sarcopenia is thought to be related to the microbiome, but not enough reports in chronic liver disease (CLD) patients. In addition to the differences in microbiome, the role of the microbiome in the gut is also important to be clarified because it has recently been shown that the microbiome may produce branched-chain amino acids (BCAAs) in the body. In this single-center study, sixty-nine CLD patients were divided by skeletal muscle mass index (SMI) into low (L-SMI: n = 25) and normal (N-SMI: n ...[more]
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