Molecular characterization of Trypanosoma cruzi DTUs of the triatomine species in a Chagas disease endemic area.

ABSTRACT: Trypanosoma cruzi is the etiological agent of Chagas disease, a neglected tropical infection with great public health importance. This protozoan has triatomine insects as vector but may also be transmitted through blood transfusion, organ transplants, ingestion of contaminated food, or congenitally. It has a heterogeneous population classified into Discrete Typing Units (DTUs), TcI-TcVI and TcBat. The aim of this study was to molecularly characterize the DTUs of T. cruzi in triatomines from a Chagas disease endemic area in Northeastern Brazil. Triatomines were collected and the gut content was microscopically analyzed to investigate the presence of trypanosomatid flagellates. In addition, digestive tracts of some specimens were dissected and molecularly analyzed through PCR f

SUBMITTER: Silva TRM 

PROVIDER: S-EPMC8901897 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature